Detalhe da pesquisa
1.
RAS Proteins and Their Regulators in Human Disease.
Cell
; 170(1): 17-33, 2017 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28666118
2.
Consensus on the RAS dimerization hypothesis: Strong evidence for lipid-mediated clustering but not for G-domain-mediated interactions.
Mol Cell
; 83(8): 1210-1215, 2023 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36990093
3.
Uridylation by TUT4 and TUT7 marks mRNA for degradation.
Cell
; 159(6): 1365-76, 2014 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25480299
4.
Machine learning-driven multiscale modeling reveals lipid-dependent dynamics of RAS signaling proteins.
Proc Natl Acad Sci U S A
; 119(1)2022 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34983849
5.
The ribosomal S6 kinase 2 (RSK2)-SPRED2 complex regulates the phosphorylation of RSK substrates and MAPK signaling.
J Biol Chem
; 299(6): 104789, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37149146
6.
RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity.
Proc Natl Acad Sci U S A
; 118(33)2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34380736
7.
Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane.
Proc Natl Acad Sci U S A
; 117(39): 24258-24268, 2020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32913056
8.
Exploring CRD mobility during RAS/RAF engagement at the membrane.
Biophys J
; 121(19): 3630-3650, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35778842
9.
Insights into the Cross Talk between Effector and Allosteric Lobes of KRAS from Methyl Conformational Dynamics.
J Am Chem Soc
; 144(9): 4196-4205, 2022 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35213144
10.
A phosphate-binding pocket within the platform-PAZ-connector helix cassette of human Dicer.
Mol Cell
; 53(4): 606-16, 2014 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24486018
11.
KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis.
Proc Natl Acad Sci U S A
; 116(44): 22122-22131, 2019 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611389
12.
RAS internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling.
J Biol Chem
; 295(28): 9335-9348, 2020 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393580
13.
The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1.
Mol Cancer
; 20(1): 141, 2021 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34727930
14.
Structural basis of mRNA recognition and cleavage by toxin MazF and its regulation by antitoxin MazE in Bacillus subtilis.
Mol Cell
; 52(3): 447-58, 2013 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24120662
15.
Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family.
J Biol Chem
; 293(43): 16709-16723, 2018 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30206120
16.
TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms.
EMBO J
; 34(13): 1801-15, 2015 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25979828
17.
Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature
; 500(7463): 463-7, 2013 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863933
18.
Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ.
Proc Natl Acad Sci U S A
; 113(44): E6766-E6775, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791178
19.
A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev
; 25(2): 137-52, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21245167
20.
Phosphatidylserine Stimulates Ceramide 1-Phosphate (C1P) Intermembrane Transfer by C1P Transfer Proteins.
J Biol Chem
; 292(6): 2531-2541, 2017 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28011644